Trans Organs on a Chip

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Biofabbing organs.jpg

Started at Biofabbing Convergence Fabrications & Fabulations at CERN in 2017,
the future of trans organs on a chip is coming to a space near you.
Externalized Organs for Exploration
Gonadrian Dissolution

This is a Work in Progress, please join in!

Inspiration

The Trans Organs on a Chip is a project within BIO-reSEARCH, the Pechblenda tentacles, mixed with AnarchaGland & Gynepunk biolabs.

The Trans Organs on a Chip is a project within BIO-reSEARCH, the Pechblenda tentacles that is oriented in a wide angle of actions that finally concern to the realization of Experiments, prototypes and use full technologies in order to have access to them. During the last years have been developed multiple technologies Pechblenda is one of the autonomous laboratories that experiment with aspects bio.electro.chemical and investigations for the development of strategies that reinforce the degree of “autonomy”. .Biohacking network, Hackteria as transhackfeminist biopunk network, we have not stopped doing together and collaborating with the extended network.

The project was an idea of Paula Pin and has been joined by many others who are interested!

Motivations

Motivations for the project is plural.

Microfluidics?

The inspiration came from this paper A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle by Xia et al, 2017 published in Nature Communications (doi:10.1038/ncomms14584).


Biofabbing figure from paper.jpg

Version one started at CERN (CH) late night at the Biofabbing Convergence (May 2017), then continued at the Co-Lab Microfluidics Workshop Featuring Digital Microfluidics and Cell Squeezers! (June 2017) by the Open Science School at CRI in Paris (FR).
Co-lab microfluidics.jpg Co-lab microfluidics official.jpg

TransOrgansonaChip works as an hybrid entity between microfluidic device and a bioreactor, Trans.Organ.on.a.Chip is built into an experimental setup that has different cavities to hold human-plant cells, hormones, plants and cyanobacteria extracts. The hybrid chip is immersed with the coevolution of macro molecules of cells that evolve in dependence of each other, rather than towards an approximation to a fitness optimum. This coevolution of cells, hormones and novel culture media is made of polysacaride extraction of cyanobacteria Spirulina, new living media that not only speculates about possible futures but also allows the resource to be used in the most sustainable metabolic pathway. By focusing on the use of this ancient microorganism as a green chemistry tool that prevents the growth of carcinogens, we enact the process of decolonizing western medicine and reductionist science.

Cervixonachip001.jpg TransOrgans003.jpg

First we start to draw all the organs related with sexuality. 

Cervixonachip00.jpg CervixonaChip002.jpg

Them we use the PDMS to cast the organs.

Current Status

Organs

2D or 3D?

Valves

Electromagnetic

Pneumatic

References

Documentation

  • Video from the Co-Lab microfluidics Workshop final wrap up session on a poster.